Descrizione Clinica
Digestion Hepatoguna 32cpr swallowable
Hepatoguna
Description
Food supplement nutraceutical, with neorland liver lyophilisate, choline and green tea, thanks to its trophic activity on liver parenchyma, antioxidant and detoxifying, finds application as food support in support of liver function.
Ingredients
Charge officer: microcrystalline cellulose (cellulose gel); lyophilized pig liver, choline bitartrate; anti-agglomerating agents: fatty acids, silicon dioxide, reticulated sodium carbossimetilcellulose; green tea (Camellia sinensis L. Kuntze, leaves) dry extract tit to 40% in epigallocatechinagallato (EGCG); anti-agglomerating agents: polyvinylpolypyrrolidone, magnesium salts of fatty acids; coating agent: etylcellulose; coloring: iron oxide; anti-agglomerating agent: talc; coating agent: caranuba wax.
Nutritional characteristics
Mode of use
Take 1 pill swallowable 2 times a day; swallow the tablet with water. We recommend taking for at least 2 consecutive months.
Warnings
Do not exceed the recommended daily dose. Keep out of reach of children under three years of age. We do not recommend use in pregnancy. Supplements should not be understood as substitutes for a varied, balanced diet and healthy lifestyle.
Conservation
Store the product in a cool and dry place, protected from light and heat sources. The expiry date refers to the correctly stored product, in a package.
Format
Pack of 32 swallowable tablets of 1,13 g.
Net weight: 36,16 g.
Bibliography
1. Ferroni O, Tassinari R et al. Epatoguna. – Neorland® pig liver lyophilisate is a source of well-preserved and biologically active hexosomes on human stem cells. Med. Biol., 2019/1; 3-9.
2. Fukuda Y et Al. “Effect of hydrolysate on hepatic proliferation in regenerating rat liver” Nihon Yakurigaku Zasshi. 1999 Oct;114(4):233-8.
3. Nishikawa T., Bell A., Locker J., et al. Resetting the transcription factor network reverses terminal chronic hepatic failure. J Clin Invest. 2015 Mar 16.
4. Takahashi K, et al. Induction of pluripotent coat of arms cells from adult human fibroblasts by defined factors. - Cell. 2007
5. Christ B. et Al. “Implication of hepatic coat of arms cells in functional liver repopulation”; Cytometry Part A .83A: 90,102; 2013
6. Herrera MB. et Al. “Human stem cell derived microvesicles accelerated hepatic regeneration in hepatectomized rats”; J.Cell.Mol.Med.Vol 14, n.6B,2010 pp.1605-16189
7. Eirin et Al. “MicroRNA and mRNA cargo of extracellular vesicles from porcine adipose tissue-derived mesenchymal coat of arms cells” Gene 551 (2014) 55-64
8. Peng D. et Al. “The tetraspanin CD151-ARSA mutant inhibits angiogenesis via the YRSL sequence” Molecular Medicine Reports 7: 836-842; 2013
9. Fatemeh Momen-Heravi et Al. “Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensotize monocytes to LPS” www.nature.com/scientificreports May 2015
10. Corbin K.D., Abdelmalek M.F., Spencer M.D., et Al. “Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis.” FASEB J. 2013 [Epub ahead of print]. fj.12-219097.
11. Bose M., Lambert J.D., Ju J, Reuhl K.R., Shapses S.A., et Al. (2008) “The major green tea polyphenol, (2)- epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.” J Nutr.; 138: 1677–1683.
Food supplement nutraceutical, with neorland liver lyophilisate, choline and green tea, thanks to its trophic activity on liver parenchyma, antioxidant and detoxifying, finds application as food support in support of liver function.
Ingredients
Charge officer: microcrystalline cellulose (cellulose gel); lyophilized pig liver, choline bitartrate; anti-agglomerating agents: fatty acids, silicon dioxide, reticulated sodium carbossimetilcellulose; green tea (Camellia sinensis L. Kuntze, leaves) dry extract tit to 40% in epigallocatechinagallato (EGCG); anti-agglomerating agents: polyvinylpolypyrrolidone, magnesium salts of fatty acids; coating agent: etylcellulose; coloring: iron oxide; anti-agglomerating agent: talc; coating agent: caranuba wax.
Nutritional characteristics
| Average values | for 100 g | for 2 tablets |
| Energy | 1.263 kJ 306,3 kcal | 28,44 kJ 6,89 kcal |
| Fats of which saturated | 14.3 g 12,64 g 4.2 g | 0.32 g 0.28 g |
| Carbohydrate of which sugar | 1,4 g 0.3 g | 0.03 g 0.01 g |
| Protein | 23 g | 0.5 % g |
| Rooms | 0,63 g | 0.01 g |
| Lyophilized liver | 26,67 g | 600 mg |
| Colina | 7,33 g | 165 mg |
| Tea green dry extract of which EGCG | 1,78 g 0,71 g | 40 mg 16 mg |
Mode of use
Take 1 pill swallowable 2 times a day; swallow the tablet with water. We recommend taking for at least 2 consecutive months.
Warnings
Do not exceed the recommended daily dose. Keep out of reach of children under three years of age. We do not recommend use in pregnancy. Supplements should not be understood as substitutes for a varied, balanced diet and healthy lifestyle.
Conservation
Store the product in a cool and dry place, protected from light and heat sources. The expiry date refers to the correctly stored product, in a package.
Format
Pack of 32 swallowable tablets of 1,13 g.
Net weight: 36,16 g.
Bibliography
1. Ferroni O, Tassinari R et al. Epatoguna. – Neorland® pig liver lyophilisate is a source of well-preserved and biologically active hexosomes on human stem cells. Med. Biol., 2019/1; 3-9.
2. Fukuda Y et Al. “Effect of hydrolysate on hepatic proliferation in regenerating rat liver” Nihon Yakurigaku Zasshi. 1999 Oct;114(4):233-8.
3. Nishikawa T., Bell A., Locker J., et al. Resetting the transcription factor network reverses terminal chronic hepatic failure. J Clin Invest. 2015 Mar 16.
4. Takahashi K, et al. Induction of pluripotent coat of arms cells from adult human fibroblasts by defined factors. - Cell. 2007
5. Christ B. et Al. “Implication of hepatic coat of arms cells in functional liver repopulation”; Cytometry Part A .83A: 90,102; 2013
6. Herrera MB. et Al. “Human stem cell derived microvesicles accelerated hepatic regeneration in hepatectomized rats”; J.Cell.Mol.Med.Vol 14, n.6B,2010 pp.1605-16189
7. Eirin et Al. “MicroRNA and mRNA cargo of extracellular vesicles from porcine adipose tissue-derived mesenchymal coat of arms cells” Gene 551 (2014) 55-64
8. Peng D. et Al. “The tetraspanin CD151-ARSA mutant inhibits angiogenesis via the YRSL sequence” Molecular Medicine Reports 7: 836-842; 2013
9. Fatemeh Momen-Heravi et Al. “Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensotize monocytes to LPS” www.nature.com/scientificreports May 2015
10. Corbin K.D., Abdelmalek M.F., Spencer M.D., et Al. “Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis.” FASEB J. 2013 [Epub ahead of print]. fj.12-219097.
11. Bose M., Lambert J.D., Ju J, Reuhl K.R., Shapses S.A., et Al. (2008) “The major green tea polyphenol, (2)- epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.” J Nutr.; 138: 1677–1683.
