BRUNIZINA GTT NAS 10ML 0.2%

BRUNIZATION

active ingredients

100 ml of nebulized solution and 100 ml of drops contain: Active ingredient: Nafazolina Hydrochloride g 0.200. For excipients see paragraph 6.1.

Excellent

p-oxybenzoic esters, purified water.

Therapeutic indications

Decongestant in nasal, paranasal and nasopharynx processes.

Contraindications

Hypersensitivity and product components. Chronic rhinitis. Heart disease and severe arterial hypertension. Hyperthyroidisms. Glaucoma. Prostate hypertrophy. The drug is contraindicated in children under the age of 12. Do not administer during or in the two weeks following therapy with monoaminoxydase inhibitors. Do not take it by mouth. Do not use for more than four consecutive days.

Population

- solution drops: three-four drops for endo-nasal instillations, two or three times a day. For nasal aerosols and pharynx: dilute a part of solution in two parts of distilled water; - nebulized solution: three endo-nasal nebulizations, two or three times a day. Strictly stick to the recommended doses. A higher dose of the product even if taken in a topical way and for a short period of time can give rise to serious systemic effects.

Conservation

Store at temperature not exceeding 30 °C.

Warnings

The product, if accidentally ingested, can determine toxic phenomena. Keep out of reach and sight of children. In patients with cardiovascular diseases, and especially in hypertensives, the use of nasal decongestants must be subjected to the doctor’s judgment. Protracted use of vasoconstrictors can alter the normal function of nasal mucosa and paranasal breasts, also inducing drug addiction. Application repetition for long periods of time may be harmful. Therefore, if you do not appreciate favourable results within a few days from the beginning of the treatment, suspend the use of the preparation and consult your doctor. Bounce congestion is frequent with the use of nasal decongestants, and can lead, with vicious circle, to excessive use of the product: therefore with scruple to the recommended doses. Overdose cases are more frequent and more severe in children. Particular caution should be taken in children, the elderly and women in the first months of pregnancy. For children and sensitive persons it is appropriate to administer the preparation to a concentration of 0.50 per thousand, adding, that is, to a part of Brunizina three parts of water.

Interactions

They're not known.

Effects

The product can cause locally phenomena of intolerance or mucosal rebound congestion. For high-dose treatments or extended therapies over four days, the absorption of nafazoline through inflamed mucosa can determine systemic effects consisting of arterial hypertension, reflex bradycardia, headache, urination disorders. In case of overdose, as in case of accidental orally intake, arterial hypertension, tachycardia, sense of chest oppression, intense headache and, in children, hypothermia, depression of the central nervous system with marked sedation, these symptoms requiring the application of adequate emergency measures.

Overdosing

Do not exceed the indicated doses, in order to avoid side effects, such as bradycardia, drowsiness, damage to the nasal mucosa.

Particular caution in the use of the product must be taken during the first months of pregnancy and during the lactation period.

Source: Farmadati