PSORADINE

Food supplement based on Omega 3, vitamins and mineral salts to be used as a coadjuvant in some pathological conditions such as psoriasis.
In the patient with psoriasis, the administration of Omega 3 (alpha linolenic acid, EPA, DHA) in conjunction with the standard topical and/or systemic treatments, is able to:
- Decrease the production of pro-inflammatory cytokines. (1,4)
- Determining a significant improvement in total PASI. (1)
- Extend the benefits of phototherapy. (6)
- Reduce the nephrotoxicity of Ciclosporin. (6)
- Reduce hyperlipidemia induced by the use of systemic retinoids. (6)
Vitamin A and D
They can inhibit the proliferation of keratinitis and stimulate the differentiation of immature ones. (7)
Vitamin E
With antioxidant and anti-radical action particularly high in all chronic inflammatory processes. (8)
Uncle, Selenium, and Chromium
Components of important enzymatic complexes essential for maintaining the normal functions of the skin and the immune system. (9)
Useful in all patients with psoriasis or arthritis, both in treatment with topical and/or systemic therapies, and not treated.

Ingredients
Flaxseed oil (linum usestatissimum); concentrated fish oil; food jelly; resistance agent: glycerol; thickener: colloidal silica; zinc gluconate; dl-alpha-tocoferil acetate (vitamin and acetate); Antiagglomerating: E555; Vitamin A palmitato 1 M UI/g (Retinol in sunflower oil); chloride chloride; vitamin D3 1M UI/g ( Colecalciferol in medium chain triglycerides); sodium selenito; colorants:E172.

Mode of use
Take 2 capsules per day.

Warnings
Do not exceed the recommended daily dose.
Keep out of reach of children under 3 years of age.
Supplements should not be understood as substitutes for a varied diet.
For pregnant or breastfeeding women and children it is recommended to feel the medical advice.

Conservation
Store in a cool and dry place, sheltered from sources of light and heat.

Nutritional characteristics

	for 2 capsules	%RDA*
Energy value	16,814 kcal 69,530 kj
Protein	0,472 g	-
Carbohydrate	0.240 g	-
Fats of which: Saturated fatty acids Monounsaturated fatty acids Polyunsaturated fatty acids of which Linolenic acid EPA DHA 0mega 3	1.552 g 0.060 g 0.102 1.372 0,600 g 0,282 0.188 g 1,100 g
Vitamin E	10 mg-á-TE	83,3
Vitamin A	800 mcg-RE	100
Vitamin D	5 mc	100
Zinc	11,25 mg	112,5
Chrome	150 mc	375
Selenium	75 mc	136,4
Flax oil	0,858 g
Fish oil	0,694 g

*RDA: recommended daily dose.

Format
Pack of 45 capsules.

Bibliography
-1 Mayser P., et All. “n fatty acid in psoriasis”, Br. J. Nutr. 2002, Jan;87 Suppl 1:S77-82 2 - Staberg et all. “Abnormal vitamin D metabolism in patients with psoriasis”. Acta Derm Venereol. 1987;67(1) 65-68.
-3 McMillan et all. “ Plasma galvanized in psoriasis:relation to surface area involvement” Br.J.Dermatol. 1983;108 (3):301-305 4 - Artemis P. et all. “Omega 3 fatty acids in inflammation and autoimmune diseases”. J.Am. College of Nutr. Vol. 21 n° 6, 495-505 (2002).
-5 Simopoulos AP. “The omega 6/omega 3 fatty acid ratio, genetic variation and cardiovascular disease”. Asia Pac. J. Clin. Nutr.,2008; 17 suppl. 1:131-134.
-6 Simopoulos AP. “Omega 3 fatty acids in health and disease and in growth and development”. Am. J. Clin. Nutr. 1991;54:438-463.
-7 Lehmann B. et all.” Vitamin D and skin: new aspects for dermatology”. Exp. Dermatol. 2004; 13 suppl. 4:11-15.
-8 Corrocher et all.”Effect of fish oil supplementation on erythrocyte lipid pattern in psoriasis” Clin. Chim. Acta, 1989, Feb. 15;179(2):121-131.
-9 Maggini et all.”Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular humoral immune response”. J. Nutr. 2007 Oct; 98 Suppl. 1:s29-35.