Descrizione Clinica
SCREEN
DRUG TESTING
Synthetic drugs
K2 Spice
Instructions for use for each combination of tests of the following drugs: amphetamine, benzodiazepine, cocaine, marijuana, methyldioxytamphetamine, ketamine, opioids, synthetic marijuana k2/spice.
Monophase tests for the simultaneous determination of drugs and their metabolites in human urine.
Precautions
Product not intended for medical or diagnostic use.
Do not use it beyond the expiry date.
Store the reactive strip panel in the closed enclosure until use.
All samples must be considered potentially dangerous and therefore must be manipulated with precautions of use relating to potentially infectious products.
After use, the panel must be deleted according to the local rules in force.
Store in the closed enclosure at a temperature between 2nd and 30°C.
The reactive strip panel is stable until the expiry date indicated on the wrapping label.
The reactive strip panel must be kept in the closed enclosure until the time of use.
Don't freeze.
Do not use it beyond the expiry date.
Expected use and summary
Screening tests for simultaneous determination of different drugs.
The rapidity and sensitivity of immunological tests have led them to be considered the most accepted as screening tests in the urine for simultaneous drug research.
The monophase test strip brush (Urina) is a lateral flow immunochromatic test for qualitative determination of the following drugs without the help of tools:
This test only provides preliminary analytical data.
More specific chemical methods must be used as confirmation of analytical result.
Preferential confirmation methods are considered for chromatography gas and mass spectrometry (GC/MS).
Any result for determining the presence of abuse drugs must be related to clinical considerations and professional judgment, especially when the preliminary result is positive.
It is a rapid screening test of urine that does not require the use of particular tools.
The test uses antibodies to selectively detect high levels of specific substances in human urine.
The time of stay is approximate for each substance as they vary according to the frequency of use, body mass, age, state of health, tolerance to the narcotic substances and the pH of urine.
The product detects the presence of narcotic substances in urine only after their metabolization.
COCAINE (COC)
Cocaine is a powerful stimulant of the central nervous system as well as local anesthetic derived from the coca plant.
The substance is often self administered by inhalation or intravenous injection or by smoking the base substance.
AMFETAMINA (AMP)
Amphetamine is a substance also used for therapeutic purposes.
The substance is often self- administered by inhalation or ingestion.
High doses produce enhanced stimulation of the central nervous system and induce euphoria, vigile state, appetite reduction, sense of greater energy and strength.
Acute reactions produce anxiety, paranoia, hallucinations and psychotic behavior.
METILDIOSSIMETAMFETAMINE (MDMA)
Ecstasy is not a stimulant, although it has in common with amphetamines the ability to increase blood pressure and heart rate.
It produces some changes in perception such as greater sensitivity to light, difficulty focusing, blurred view.
The effect that occurs practically in all those taking this substance is to tighten the jaw.
MARIJUANA (THC)
Tetrahydrocannabinol is the active ingredient of cannabis.
When smoked or taken orally, THC produces euphoria.
Regular consumers have short-term memory damage and learning delay, they can also have transient episodes of confusion and anxiety.
Long-term consumption relatively heavy can be associated with behavior disorders.
OPPIACEI (OPI)
The class of opioids refers to any substance derived from opium poppy, including natural compounds such as morphine, codeine and semisynthetic substances such as heroin.
Opiates act on pain control by depressing the central nervous system.
Astinence symptoms may include sweating, tremors, nausea and irritability.
Opiates can be taken orally or through intravenous, intramuscular and subcutaneous injection.
Consumers may also take the substance intravenously or through inhalation.
BENZODIAZEPINA (BZO)
These are frequently prescribed medications for symptomatic treatment of anxiety, sleep disorders, epileptic attacks and alcohol withdrawal syndrome.
Sudden interruption can induce symptoms such as sleeping disorders, gastrointestinal, loss of appetite, sweating, tremor, weakness, anxiety and changes in perception.
KETAMINA (KET)
Ketamina is a dissociative anesthetic for human and veterinary use.
It is marketed in Italy with the names of Ketalar, Ketanest and Ketaset and in the human field is classified as Farmaco "H" and should be used exclusively in hospital environment by an anesthesiologist-resuscitator.
Like all neuro and psycholeptic drugs, it can be abused and voluptuary use, prohibited and sanctioned by the Law, as an astonishing substance.
MARIJUANA SINTETICA K2/SPICE (K2/SPICE)
Synthetic Marijuana or K2 is a psychoactive herb and a chemical that if consumed mimes the effects of Marijuana.
Mostly known with commercial names of K2 and Spice, both widely used to refer to any synthetic product of Marijuana.
Principle
The monophase test strip panel (Urina) is a rapid immunochromatic test based on the competitive binding principle.
Drugs that may be present in the urine sample compete with its conjugate for the same antibody binding sites.
During the test, a urine sample migrates by capillaries along the membrane.
A drug, if present in the urine sample, at a lower concentration than its cut-off, will not be able to saturate all particle binding sites related to the relative antibodies present in the strip.
Antibodies tied particles will be captured by the immobilized conjugate and a visible colored band will appear in the test band area of its strip.
The colored band will not form in its area if the drug level will be higher than its cut-off, as all related antibodies binding sites will be saturated.
A positive drug urine sample will not cause colored band formation due to drug competition, while a negative urine sample to the drug under examination or a sample containing a drug concentration lower than the cut-off will cause colored band formation in the specific test area.
As a procedure control, a colored band will appear in the relative area, indicating that a correct sample amount has been used and that the migration on the membrane occurred.
Reagent
Each strip of the panel contains monoclonal antibodies of rats linked to the particles and the corresponding.
The monophase test strip panel (Urina) is a conjugated lateral flow immunochromatic test for each drug.
Goat antibodies are used for control gang.
Relief and preparation of samples
Collect urine sample in a clean and dry container.
Urine samples collected at any time of the day can be used.
The urine samples with evident presence of precipitate must be centrifuged, filtered or let deposit in order to obtain a clear sample on which to carry out the test.
Urine samples can be stored at a temperature of 2-8°C at most for 48 hours.
For prolonged storage, samples can be frozen and stored at a temperature below -20°C.
Before using frozen samples it is necessary to make them defrost and homogenize them thoroughly.
Use procedure
1. Before opening the enclosure, bring it to room temperature. Extract the product from the wrap and use it as soon as possible.
2. Remove the hood from the stripes. Dip the product vertically, towards the arrows, into the urine sample for at least 10/15 seconds. Dip the product to the level of the undulated rows on the strips but not above them.
3. Put the cap on the device and horizontally rest the product on a flat surface not absorbent. Read the result after 5 minutes. Do not interpret the result after 10 minutes.
Interpretation of results
Negative a coloured band appears in the control area (C) and a second in the reactive area (T) for each drug indicating a negative result.
The negative result indicates that the drug concentration in the urine is below the cut-off level detectable for that specific drug.
*the color shade in the reactive zone (T) may vary, but it must be considered negative whenever a weak colored band appears.
Positive: a colored band appears in the control area (C) but not in the reactive area (T) for each drug indicating a positive result.
The positive result indicates that the drug concentration in question in urine is higher than the cut-off level detectable for that specific drug.
Not valid: no control band (C).
The most plausible causes for the failure of the control band can be an insufficient sample volume or incorrect analytical process.
Recheck the process and repeat the test using a new panel.
If the problem persists immediately interrupt the use of the kit and contact the local distributor.
If the test was positive, avoid aggressive behaviour and calmly seek dialogue with the person concerned.
Please be advised by your doctor, a psychologist or contact the competent service for your territory.
Quality control
The test includes an internal control system consisting of the red band that appears in the control area (C).
The appearance of this band confirms that the test was performed correctly with a sufficient sample volume, that the absorption of the membrane was adequate and the correct procedure.
Standard controls are not provided with the kit; however it is recommended to test positive and negative controls, such as good laboratory practice, to confirm the test procedure and verify the correct characteristics.
Limits
1. The single-phase test strip panel (Urina) provides only a qualitative preliminary analytical result. It is necessary to adopt a second analytical method. Preferential confirmation methods are considered for chromatography and mass spectrometry (GC/MS) to be recommended if the test is positive.
2. It is possible that technical or procedural errors, as well as interfering substances present in the urine sample, can cause incorrect results.
3. It is possible that adulterating substances, such as bleach and/or alumen present in the urine sample may cause incorrect results regardless of the analytical method used. If you suspect the presence of such substances, the test must be repeated with another urine sample.
4. A positive result indicates the presence of drugs or metabolites but not the level of intoxication the way of administration or concentration in urine.
5. A negative result does not necessarily mean that the urine sample is drug-free. A negative result can be obtained when the drug is present but at a lower concentration than the cut-off level of the test.
6. The test is not able to distinguish between the drug and a drug containing the same positive false substance can be caused by certain drugs.
Format
• 1 urine container.
• 1 Drug Test Cocaine.
• illustrative leaflet.
Monophase tests for the simultaneous determination of drugs and their metabolites in human urine.
Precautions
Product not intended for medical or diagnostic use.
Do not use it beyond the expiry date.
Store the reactive strip panel in the closed enclosure until use.
All samples must be considered potentially dangerous and therefore must be manipulated with precautions of use relating to potentially infectious products.
After use, the panel must be deleted according to the local rules in force.
Store in the closed enclosure at a temperature between 2nd and 30°C.
The reactive strip panel is stable until the expiry date indicated on the wrapping label.
The reactive strip panel must be kept in the closed enclosure until the time of use.
Don't freeze.
Do not use it beyond the expiry date.
Expected use and summary
Screening tests for simultaneous determination of different drugs.
The rapidity and sensitivity of immunological tests have led them to be considered the most accepted as screening tests in the urine for simultaneous drug research.
The monophase test strip brush (Urina) is a lateral flow immunochromatic test for qualitative determination of the following drugs without the help of tools:
| Test | Calibrator | Cut-off (ng/ml) |
| Cocaine (COC) Amphetamine (AMP) Metildiossimetamphetamine (MDMA) Marijuana (THC) Opioids (OPI) Benzodiazepine (BZO) Ketamina (KET) Synthetic Marijuana k2/spice | benzolecnogina D-amfetamine D,L-methyldiossimetamphetamine 11-nor-Δ9-THC-9 COOH morphine Oxazepam Ketamine jwh-018 and jwh-073 | 300 1.000 500 50 2.000 300 1.000 50 |
This test only provides preliminary analytical data.
More specific chemical methods must be used as confirmation of analytical result.
Preferential confirmation methods are considered for chromatography gas and mass spectrometry (GC/MS).
Any result for determining the presence of abuse drugs must be related to clinical considerations and professional judgment, especially when the preliminary result is positive.
It is a rapid screening test of urine that does not require the use of particular tools.
The test uses antibodies to selectively detect high levels of specific substances in human urine.
The time of stay is approximate for each substance as they vary according to the frequency of use, body mass, age, state of health, tolerance to the narcotic substances and the pH of urine.
The product detects the presence of narcotic substances in urine only after their metabolization.
COCAINE (COC)
Cocaine is a powerful stimulant of the central nervous system as well as local anesthetic derived from the coca plant.
The substance is often self administered by inhalation or intravenous injection or by smoking the base substance.
AMFETAMINA (AMP)
Amphetamine is a substance also used for therapeutic purposes.
The substance is often self- administered by inhalation or ingestion.
High doses produce enhanced stimulation of the central nervous system and induce euphoria, vigile state, appetite reduction, sense of greater energy and strength.
Acute reactions produce anxiety, paranoia, hallucinations and psychotic behavior.
METILDIOSSIMETAMFETAMINE (MDMA)
Ecstasy is not a stimulant, although it has in common with amphetamines the ability to increase blood pressure and heart rate.
It produces some changes in perception such as greater sensitivity to light, difficulty focusing, blurred view.
The effect that occurs practically in all those taking this substance is to tighten the jaw.
MARIJUANA (THC)
Tetrahydrocannabinol is the active ingredient of cannabis.
When smoked or taken orally, THC produces euphoria.
Regular consumers have short-term memory damage and learning delay, they can also have transient episodes of confusion and anxiety.
Long-term consumption relatively heavy can be associated with behavior disorders.
OPPIACEI (OPI)
The class of opioids refers to any substance derived from opium poppy, including natural compounds such as morphine, codeine and semisynthetic substances such as heroin.
Opiates act on pain control by depressing the central nervous system.
Astinence symptoms may include sweating, tremors, nausea and irritability.
Opiates can be taken orally or through intravenous, intramuscular and subcutaneous injection.
Consumers may also take the substance intravenously or through inhalation.
BENZODIAZEPINA (BZO)
These are frequently prescribed medications for symptomatic treatment of anxiety, sleep disorders, epileptic attacks and alcohol withdrawal syndrome.
Sudden interruption can induce symptoms such as sleeping disorders, gastrointestinal, loss of appetite, sweating, tremor, weakness, anxiety and changes in perception.
KETAMINA (KET)
Ketamina is a dissociative anesthetic for human and veterinary use.
It is marketed in Italy with the names of Ketalar, Ketanest and Ketaset and in the human field is classified as Farmaco "H" and should be used exclusively in hospital environment by an anesthesiologist-resuscitator.
Like all neuro and psycholeptic drugs, it can be abused and voluptuary use, prohibited and sanctioned by the Law, as an astonishing substance.
MARIJUANA SINTETICA K2/SPICE (K2/SPICE)
Synthetic Marijuana or K2 is a psychoactive herb and a chemical that if consumed mimes the effects of Marijuana.
Mostly known with commercial names of K2 and Spice, both widely used to refer to any synthetic product of Marijuana.
Principle
The monophase test strip panel (Urina) is a rapid immunochromatic test based on the competitive binding principle.
Drugs that may be present in the urine sample compete with its conjugate for the same antibody binding sites.
During the test, a urine sample migrates by capillaries along the membrane.
A drug, if present in the urine sample, at a lower concentration than its cut-off, will not be able to saturate all particle binding sites related to the relative antibodies present in the strip.
Antibodies tied particles will be captured by the immobilized conjugate and a visible colored band will appear in the test band area of its strip.
The colored band will not form in its area if the drug level will be higher than its cut-off, as all related antibodies binding sites will be saturated.
A positive drug urine sample will not cause colored band formation due to drug competition, while a negative urine sample to the drug under examination or a sample containing a drug concentration lower than the cut-off will cause colored band formation in the specific test area.
As a procedure control, a colored band will appear in the relative area, indicating that a correct sample amount has been used and that the migration on the membrane occurred.
Reagent
Each strip of the panel contains monoclonal antibodies of rats linked to the particles and the corresponding.
The monophase test strip panel (Urina) is a conjugated lateral flow immunochromatic test for each drug.
Goat antibodies are used for control gang.
Relief and preparation of samples
Collect urine sample in a clean and dry container.
Urine samples collected at any time of the day can be used.
The urine samples with evident presence of precipitate must be centrifuged, filtered or let deposit in order to obtain a clear sample on which to carry out the test.
Urine samples can be stored at a temperature of 2-8°C at most for 48 hours.
For prolonged storage, samples can be frozen and stored at a temperature below -20°C.
Before using frozen samples it is necessary to make them defrost and homogenize them thoroughly.
Use procedure
1. Before opening the enclosure, bring it to room temperature. Extract the product from the wrap and use it as soon as possible.
2. Remove the hood from the stripes. Dip the product vertically, towards the arrows, into the urine sample for at least 10/15 seconds. Dip the product to the level of the undulated rows on the strips but not above them.
3. Put the cap on the device and horizontally rest the product on a flat surface not absorbent. Read the result after 5 minutes. Do not interpret the result after 10 minutes.
Interpretation of results
Negative a coloured band appears in the control area (C) and a second in the reactive area (T) for each drug indicating a negative result.
The negative result indicates that the drug concentration in the urine is below the cut-off level detectable for that specific drug.
*the color shade in the reactive zone (T) may vary, but it must be considered negative whenever a weak colored band appears.
Positive: a colored band appears in the control area (C) but not in the reactive area (T) for each drug indicating a positive result.
The positive result indicates that the drug concentration in question in urine is higher than the cut-off level detectable for that specific drug.
Not valid: no control band (C).
The most plausible causes for the failure of the control band can be an insufficient sample volume or incorrect analytical process.
Recheck the process and repeat the test using a new panel.
If the problem persists immediately interrupt the use of the kit and contact the local distributor.
If the test was positive, avoid aggressive behaviour and calmly seek dialogue with the person concerned.
Please be advised by your doctor, a psychologist or contact the competent service for your territory.
Quality control
The test includes an internal control system consisting of the red band that appears in the control area (C).
The appearance of this band confirms that the test was performed correctly with a sufficient sample volume, that the absorption of the membrane was adequate and the correct procedure.
Standard controls are not provided with the kit; however it is recommended to test positive and negative controls, such as good laboratory practice, to confirm the test procedure and verify the correct characteristics.
Limits
1. The single-phase test strip panel (Urina) provides only a qualitative preliminary analytical result. It is necessary to adopt a second analytical method. Preferential confirmation methods are considered for chromatography and mass spectrometry (GC/MS) to be recommended if the test is positive.
2. It is possible that technical or procedural errors, as well as interfering substances present in the urine sample, can cause incorrect results.
3. It is possible that adulterating substances, such as bleach and/or alumen present in the urine sample may cause incorrect results regardless of the analytical method used. If you suspect the presence of such substances, the test must be repeated with another urine sample.
4. A positive result indicates the presence of drugs or metabolites but not the level of intoxication the way of administration or concentration in urine.
5. A negative result does not necessarily mean that the urine sample is drug-free. A negative result can be obtained when the drug is present but at a lower concentration than the cut-off level of the test.
6. The test is not able to distinguish between the drug and a drug containing the same positive false substance can be caused by certain drugs.
Format
• 1 urine container.
• 1 Drug Test Cocaine.
• illustrative leaflet.
