NO STRESS

Food supplement based on 4 plant extracts (Mellissa Officinalis, Rodiola, Rosea, phosphatidylserine, Griffonia simplicifolia) that favor: calm, a suitableogenic effect (adaptation to stress), attenuate the production of cortisol (the hormone produced in stress situation that favors the decay and wear of the body) is therefore a nutritional help based on natural active ingredients to be included in the diet, in a healthy environment, for those who want help against stress and sleep quality.
Melissa Officinalis
Some researches indicate that 600 mg of Melissa Officinalis have improved the perception of the feeling of relaxation and calm in treated patients.^1-2
Rodhiola Rosea
Some scientific research has shown that only 50 mg of Rodhiola Rosea have caused stress reduction in treated students.
Another research has shown that 170 mg of Rodhiola Rosea extract are effective in reducing stress-induced fatigue.
A study published in the prestigious International Journal of Sport Nutrition and Exercise Metabolism has proven that 200 mg of this extract can even improve sports performance.^3-4-5
Griffonia Simplicifolia (5-htp 20%)
The seeds of griffonia contain large amounts of 5-HTP (5-hydroxytriptophan), a direct precursor of the serotonin nuerotransmitter, which regulates the sensations of well-being, pleasure, happiness and sleep.
A study assessed the clinical effectiveness of L-5-hydroxytriptophan (5-HTP) in subjects with high stress levels. Participants were given 60 mg of Griffonia simplicifolia extract at 20%. A significant improvement in stress scores has been observed through a questionnaire.^{6-7-8- 9}
Phosphatidylcholine
Research indicates that Fosfatidilserine is able to decrease cortisol levels, stress hormone with countless negative effects.
Studies indicate that 300-400 mg of phosphatidylsein improve behavioral, humoral and cognitive aspects in treated subjects and decreased symptoms of anxiety and depression.^10-11-12

Ingredients

Mode of use
To combat stress, take 2 capsules in the morning with a glass of water.
To facilitate a better sleep, take 2 capsules an hour before bedtime.

Warnings
Do not exceed the recommended doses, read warnings on the label.
Keep out of reach of children under 3 years of age.
Supplements should not be understood as substitutes for a varied diet.
For pregnant or breastfeeding women and children it is recommended to feel the medical advice.

Format
60 capsule bottle.

Bibliography:
-1 Pharmacology Biochemistry and Behavior Volume 72, Issue 4, July 2002, Pages 953-964 Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm).
-2 Psychosomatic Medicine 66:607-613 (2004)- 2004 American Psychosomatic Society - Attenuation of Laboratory-Induced Stress in Humans After Acute Administration ofMelissa officinalis (Lemon Balm)).
-3 Phytomedicine, Vol. 7(2), pp. 85-89 A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
-4 Phytomedicine, Vol. 7(5), pp. 365-371 Rhodiola rosea in stress induced fatigue - A double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy surgerys during night duty.
-5 Int J Sport Nutr Exerc Metab. 2004 Jun;14(3):298-307. Acute Rhodiola rosea intake can improve endurance exercise performance.
-6 Pharmacology Biochemistry and Behavior Volume 77, Issue 1, January 2004, Pages 137-143 5- Hydroxy-tryptophan suppresses food intake in food-deprived and stressed rats.
-7 Griffonia Seed and 5-HTP (5-hydroxy tryptophan),the magic seed from African folk medicine not only play as effective replacement for tryptophan,but more.
-8 Phytomedicine. 2011 Jul 15;18(10):848-51. Epub 2011 Feb 25. Anxiolytic-like effect of Griffonia simplicifolia Baill. seed extract in rats.
-9 Emanuele E, Bertona M, Minoretti P, Geroldi D. An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress. Neuro Endocrinol Lett. 2010;31(5):663-6.
-10 J Int Soc Sports Nutr. 2008; 5: 11. Published online 2008 July 28. The effects of phosphatidylserine on endocrine response to moderate intensity exercise.
-11 Cenacchi T, Bertoldin T, Farina C, et al. Cognitive decline in the elderly: a doubleblind, placebo-controlled multicenter study on efficacy of phosphatidylserine administration. Aging (Milan) 1993;5:123- 133.
-12 May M, Picotti GB, Bondiolotti GP, et al. Alternative Medicine Review - Volume 4, Number 3 1999 Page 159 Effects of phosphatidylserine therapy in geriatric patients with depressive disorders.