GLICEROLO AD 18SUPP 2250MG

GLICEROLO ADULTS 2250 MG SUPPOSED

active ingredients

Each suppository contains: Active ingredient: glycerol 2250 mg. For the full list of excipients, see paragraph 6.1.

Excellent

Sodium stearate, sodium bicarbonate.

Therapeutic indications

Short-term treatment of occasional constipation

Contraindications

- Hypersensitivity to the active ingredient or any of the excipients listed in paragraph 6.1; - Acute or unknown abdominal pain; - Nausea or vomit; - Obstruction or intestinal stenosis; - Rectal bleeding of unknown origin; - Hemorrhoidal crisis acute with pain and bleeding; - Severe dehydration.

Population

Population: The correct dose is sufficient to produce an easy evacuation. It is advisable to initially use the minimum doses provided. Adults and teenagers (12-18 years): 1 supposed to need, for a maximum of 1 or 2 administrations per day. Pediatric population: In children under 12 years the medicine can only be used after consulting the doctor. Method of administration: Remove the suppository from its container and then, if necessary, moisten it to facilitate the rectal introduction. If the suppositories appeared soft dip the containers, before opening them, in cold water. Laxatives must be used as frequently as possible and for no more than seven days (see paragraph 4.4). A fluid-rich diet promotes the effect of the medicine.

Conservation

Store in the original packaging to protect the medicine from moisture and away from direct sources of heat.

Warnings

Laxatives must be used as frequently as possible and for no more than seven days. Use for longer periods requires the doctor’s prescription after adequate evaluation of the individual case. Treatment of chronic or recurring constipation always requires medical intervention for diagnosis, prescription of drugs and surveillance during therapy. You should also consult your doctor before using the medicine. The abuse of laxatives can cause persistent diarrhea resulting in water loss, mineral salts (especially potassium) and other essential nutrients. In severe cases of abuse, dehydration or hypopotassiemia may occur, which may result in cardiac or neuromuscular dysfunctions, especially in the case of contemporary treatment of heart glycosides, diuretics or corticosteroids. The abuse of laxatives, especially those of contact (stimulating laxatives), can cause dependence (and, therefore, possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atonia). In episodes of constipation, it is recommended first of all to correct food habits by integrating the daily diet with an adequate supply of fiber and water. When using laxatives it is appropriate to drink at least 6-8 glasses of water per day, or other liquids, so as to facilitate the softening of stools. Pediatric population: There are no available data.

Interactions

Specific interaction studies have not been carried out.

Effects

Below are the undesirable effects of glycerol organized according to the organic systemic classification MedDRA. No sufficient data is available to determine the frequency of the individual effects listed. Gastrointestinal diseases: Insulated cramping pains or abdominal colic and diarrhea, with loss of liquids and electrolytes, more frequent in cases of severe constipation, as well as rectal irritation. Pediatric population: There are no available data Reporting of suspicious adverse reactions. The reporting of suspicious adverse reactions that occur after the authorization of the medicinal product is important, as it allows continuous monitoring of the benefit/risk ratio of the medicinal product. Healthcare professionals are required to report any adverse reaction suspected through the national reporting system of the Italian Pharmaco Agency at: http://www.aifa.gov.it/content/segnalazioni-reazioni-avverse.

Overdosing

No overdose symptoms are known under normal conditions. In any case, excessive doses (abuse of laxatives - frequent or prolonged use or with excessive doses) can cause abdominal pain, persistent diarrhea resulting in water loss, mineral salts (especially potassium) and other essential nutrients. Liquid and electrolyte losses must be replaced. Electrolytic imbalances are characterized by the following symptoms: thirst, vomiting, weakening, edema, bone pain (osteomalacia) and hypoalbuminemia. In the most serious cases, dehydration or hypopotassiemia may occur, which may cause heart or neuromuscular dysfunction, especially in the case of contemporary treatment with cardiac, diuretic, or corticosteroid glycosides. The abuse of laxatives, especially those of contact (stimulating laxatives), can cause dependence (and, therefore possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atony).

No adequate and well-controlled studies have been carried out on the use of the medicinal product during pregnancy or breastfeeding. Although there are no obvious contraindications of the use of the medicinal product in pregnancy and during breastfeeding, it is recommended to take the medicine only if necessary and under medical supervision.

Source: Farmadati